Na njem nke ịchụso ahụike na igbu oge ịka nká, nchọpụta sayensị na-ewetara anyị olileanya na ohere ọhụrụ mgbe niile. N'afọ ndị na-adịbeghị anya, NMN (Nicotinamide Mononucleotide), ihe na-eme ihe na-eme ihe ndụ nke a na-akwanyere ùgwù, ejirila nke nta nke nta bata n'anya ọha ma dọta uche zuru ụwa ọnụ. Gịnị bụ kpọmkwem? Gịnịkwa mere o ji mee ka ihe na-agụsi agụụ ike dị otú ahụ na ngalaba ahụ ike? Ka anyị tụba n'ime ihe omimi nke NMN ọnụ.
●Gịnị bụ NMN?
NMN, ya bụ Nicotinamide Mononucleotide, bụ molekul dị adị n'ụdị ndụ niile. N'ime ahụ mmadụ, NMN bụ isi mmalite maka njikọ nke coenzyme I (NAD +). Coenzyme I (NAD +) na-ekere òkè n'ọtụtụ mmeghachi omume metabolic dị mkpa n'ime sel ma na-arụ ọrụ dị mkpa n'ịkwado ọrụ nkịtị na ume nke sel. Ka ndị mmadụ na-akawanye nká, ọkwa NAD + na ahụ mmadụ ji nwayọọ nwayọọ na-ebelata, nke a kwenyere na ọ nwere njikọ chiri anya na ọtụtụ mgbanwe anụ ahụ metụtara ịka nká na ihe omume na mmepe nke ọrịa. Ịgbakwunye NMN nwere ike ịbawanye ọdịnaya nke NAD + n'ime ahụ nke ọma, si otú a na-enye nkwado ike zuru oke maka ọrụ nkịtị nke mkpụrụ ndụ ma na-enyere aka ịnọgide na-eto eto nke ahụ..
● Ụkpụrụ ọrụ nke NMN
Usoro ihe omume nke NMN na-atụgharịkarị n'ọkwa ya nke ọkwa NAD +. Mgbe anyị na-etinye NMN, ahụ na-etinye ya ngwa ngwa wee gbanwee ya na NAD + n'okpuru usoro nke usoro enzymes. Dị ka coenzyme maka ọtụtụ enzymes isi, NAD + na-ekere òkè na usoro physiological dị mkpa n'ime sel, dị ka metabolism ike, nrụzi DNA, na usoro okwu mkpụrụ ndụ ihe nketa. N'ihe gbasara metabolism ike, NAD + na-etinye aka na usoro iku ume cellular, na-enyere mitochondria aka ịtụgharị nri ka ọ bụrụ ATP, molecule ume nke mkpụrụ ndụ nwere ike iji mee ihe ozugbo. Ọkwa NAD + zuru oke na-enye aka kwalite ọrụ na arụmọrụ nke mitochondria, na-enyekwu ume maka mkpụrụ ndụ ma na-enyere anyị aka inwe ume na ike dị ukwuu. N'akụkụ nke nrụzi DNA, NAD + bụ ihe dị mkpa maka ezinụlọ PARP (Poly ADP - Ribose Polymerase). Mgbe mkpụrụ ndụ mebiri site na ụzarị ultraviolet, nrụgide oxidative, wdg, a na-arụ ọrụ enzymes PARP wee jiri NAD + mee PAR (Poly ADP - Ribose), wee weta protein ndị metụtara iji rụkwaa DNA mebiri emebi. Ịnọgide na-enwe ọkwa dị elu nke NAD + nwere ike ịkwalite ọrụ nke enzymes PARP, mee ka usoro nrụzi DNA dịkwuo elu, belata mkpokọta mkpụrụ ndụ ihe nketa na mmebi cell, ma nyere aka gbochie ihe omume nke ịka nká - ọrịa ndị metụtara ya. Na mgbakwunye, NAD + sokwa na nhazi nke ezinụlọ protein Sirtuins. Ndị na-edozi Sirtuins na-arụ ọrụ dị mkpa na ịka nká cell, usoro metabolic, nzaghachi mkpali, wdg. Dị ka coenzyme nke Sirtuins, NAD + nwere ike ime ka protein Sirtuins rụọ ọrụ, na-edozi okwu mkpụrụ ndụ ihe nketa, ma na-emetụta ọrụ physiological na ndụ nke mkpụrụ ndụ. Site n'ịgbakwụnye NMN iji mụbaa ọkwa NAD +, ọ nwere ike mee ka protein Sirtuins rụọ ọrụ na-apụtaghị ìhè ma rụọ ọrụ dị ka igbu oge ịka nká na imeziwanye ọrụ metabolic.
●Irụ ọrụ NMN
1: Na-egbu oge senescence
Usoro nke ịka nká na-esonyere na nwayọọ nwayọọ nke ọrụ nke akụkụ ahụ na usoro dị iche iche n'ime ahụ. NMN na-egbu oge usoro ịka nká na ọkwa cellular site na ọtụtụ ụzọ dị ka ịba ụba NAD +, melite ọrụ mitochondrial, ịkwalite ikike nrụzi DNA, na ịgbalite protein Sirtuins. Nnyocha na-egosi na imeju na NMN nwere ike imeziwanye ọrụ anụ ahụ nke anụmanụ na-anwale, dị ka ịkwalite ike anụ ahụ, ime ka ntachi obi dịkwuo elu, na ịkwalite ọrụ ọgụgụ isi, na-eme ka ha pụta ma na-akpa àgwà n'ọnọdụ ndị dị obere. Maka ụmụ mmadụ, mgbakwunye ogologo oge na NMN na-atụkwa anya na ọ ga-egbu oge ịka nká, belata ọdịdị wrinkles na ntụpọ afọ, melite ogo ụra, ma kwalite ọkwa ahụike zuru oke nke ahụ, na-enye anyị ohere ịnọgide na-enwe ịdị mma na ịdị ike.
2: kwalite ọgụ
NMN nwere mmetụta nchịkwa dị mma na usoro ahụ ji alụso ọrịa ọgụ. N'otu aka ahụ, ọ nwere ike ịkwalite mmụba na ọdịiche nke mkpụrụ ndụ na-alụso ọrịa ọgụ, kwalite ọrụ nke mkpụrụ ndụ na-alụso ọrịa ọgụ, ma melite ikike nzaghachi nke ahụ. N'aka nke ọzọ, NMN na-enyere aka ịnọgide na-arụ ọrụ nkịtị nke mitochondria na sel ndị na-alụso ọrịa ọgụ, na-enye nkwado ume zuru oke maka ọrụ nke mkpụrụ ndụ na-alụso ọrịa ọgụ. Site n'itinye mgbakwunye na NMN, anyị nwere ike ịkwalite mgbochi nke onwe anyị, belata ihe ize ndụ nke ọrịa, ma nagide ihe ịma aka nke gburugburu mpụga.
3:Melite ọrụ metabolic
Arụ ọrụ nke metabolic bụ ihe na-akpata ọtụtụ ọrịa na-adịghị ala ala, dịka oke ibu, ọrịa shuga, ọrịa obi, na ihe ndị ọzọ. NMN nwere ike imeziwanye ọrụ metabolic site na ịhazi ụzọ metabolic n'ime sel. Nnyocha achọpụtala na mgbakwunye na NMN nwere ike ime ka mmetụta insulin dịkwuo elu, kwalite nnabata na ojiji nke glucose, ma nyere aka ịnọgide na-enwe nkwụsi ike shuga dị n'ọbara. N'otu oge ahụ, NMN nwekwara ike ịkwalite metabolism abụba, belata mkpokọta abụba n'ime ahụ, ma na-ekere òkè dị mma n'igbochi na ịkwalite oke ibu. Tụkwasị na nke ahụ, NMN nwere mmetụta nchebe na usoro obi. Ọ nwere ike belata ọkwa lipid ọbara, melite ọrụ endothelial vaskụla, ma belata ohere nke ọrịa obi. Maka ndị na-eche banyere ahụike metabolic, NMN doro anya na ọ bụ mgbakwunye nri nwere uru bara uru.
4:Melite ọrụ ọgụgụ isi
Site na ntolite nke afọ, ọrụ ụbụrụ na-eji nwayọọ nwayọọ na-ebelata, ebe nchekwa na-ebelata, nsogbu ọgụgụ isi na nsogbu ndị ọzọ na-enwewanye nsogbu ndị agadi. NMN egosila nsonaazụ na-ekwe nkwa na ịkwalite ọrụ ọgụgụ isi.
Kpọtụrụ: Judy Guo
WhatsApp/anyị kparịta ụka:+86-18292852819
E-mail:sales3@xarainbow.com
Oge nzipu: Mar-29-2025